mouse RNF168 Adenovirus
This is an Adenovirus expressing Mouse Rnf168.
ADV-270707
Ad-m-RNF168
Ready-to-use Adenovirus expressing Mouse Rnf168 (ring finger protein 168). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
3110001H15Rik
Description (Vector)
E3 ubiquitin-protein ligase required for accumulation of repair proteins to sites of DNA damage. Acts with UBE2N/UBC13 to amplify the RNF8-dependent histone ubiquitination. Recruited to sites of DNA damage at double-strand breaks (DSBs) by binding to ubiquitinated histone H2A and ubiquitinates histone H2A and H2AX, leading to amplify the RNF8-dependent H2A ubiquitination and promoting the formation of 'Lys-63'-linked ubiquitin conjugates. This leads to concentrate ubiquitinated histones H2A and H2AX at DNA lesions to the threshold required for recruitment of TP53BP1 and BRCA1.
Gene ID
70238
Gene Name (Vector)
ring finger protein 168
Gene Symbol
Rnf168
ORF Size (aa)
1596
ORF Size (bp)
1596 bp
RefSeq ID
NM_027355
RefSeq Synonyms
NM_027355, BC046815,
Species
mouse
UniGene ID
Mm.228263
Recently Viewed Products
AAV-m-CHRDL2-shRNA
Cat No: shAAV-255435
AAV-h-NTRK3
Cat No: AAV-217167
AAV-m-ITSN1-shRNA
Cat No: shAAV-262495
Ad-m-GPR68-shRNA
Cat No: shADV-260656
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.