mouse RALA Adenovirus
This is an Adenovirus expressing Mouse Rala.
ADV-270091
Ad-m-RALA
Ready-to-use Adenovirus expressing Mouse Rala (v-ral simian leukemia viral oncogene A (ras related)). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
3010001O15Rik; AW322615; Ral; Rasl1
Description (Vector)
Multifuntional GTPase involved in a variety of cellular processes including gene expression, cell migration, cell proliferation, oncogenic transformation and membrane trafficking. Accomplishes its multiple functions by interacting with distinct downstream effectors. Acts as a GTP sensor for GTP-dependent exocytosis of dense core vesicles. Plays a role in the early stages of cytokinesis and is required to tether the exocyst to the cytokinetic furrow. The RALA-exocyst complex regulates integrin-dependent membrane raft exocytosis and growth signaling. Key regulator of LPAR1 signaling and competes with ADRBK1 for binding to LPAR1 thus affecting the signaling properties of the receptor. Required for anchorage-independent proliferation of transformed cells.
Gene ID
56044
Gene Name (Vector)
v-ral simian leukemia viral oncogene A (ras related)
Gene Symbol
Rala
ORF Size (aa)
621
RefSeq ID
NM_019491
RefSeq Synonyms
NM_019491, BC031741,
Species
mouse
UniGene ID
Mm.27348
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.