mouse RAD21 Adenovirus
This is an Adenovirus expressing Mouse Rad21.
ADV-270054
Ad-m-RAD21
Ready-to-use Adenovirus expressing Mouse Rad21 (RAD21 cohesin complex component). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
mKIAA0078; SCC1
Description (Vector)
Cleavable component of the cohesin complex, involved in chromosome cohesion during cell cycle, in DNA repair, and in apoptosis. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At metaphase-anaphase transition, this protein is cleaved by separase/ESPL1 and dissociates from chromatin, allowing sister chromatids to segregate. The cohesin complex may also play a role in spindle pole assembly during mitosis. Also plays a role in apoptosis, via its cleavage by caspase-3/CASP3 or caspase-7/CASP7 during early steps of apoptosis: the C-terminal 64 kDa cleavage product may act as a nuclear signal to initiate cytoplasmic events involved in the apoptotic pathway.
Gene ID
19357
Gene Name (Vector)
RAD21 cohesin complex component
Gene Symbol
Rad21
ORF Size (aa)
1908
ORF Size (bp)
1908 bp
RefSeq ID
NM_009009
RefSeq Synonyms
NM_009009, BC129917, BC129916, BC043032,
Species
mouse
UniGene ID
Mm.470496
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.