mouse PTPRE Adenovirus
This is an Adenovirus expressing Mouse Ptpre.
ADV-269817
Ad-m-PTPRE
Ready-to-use Adenovirus expressing Mouse Ptpre (protein tyrosine phosphatase, receptor type, E). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
PTPe; PTPepsilon; RPTPepsilon
Description (Vector)
Isoform 1 plays a critical role in signaling transduction pathways and phosphoprotein network topology in red blood cells. May play a role in osteoclast formation and function (By similarity)|Function: Isoform 2 acts as a negative regulator of insulin receptor (IR) signaling in skeletal muscle. Regulates insulin-induced tyrosine phosphorylation of insulin receptor (IR) and insulin receptor substrate 1 (IRS-1), phosphorylation of protein kinase B and glycogen synthase kinase-3 and insulin induced stimulation of glucose uptake (By similarity)|Function: Isoform 1 and isoform 2 act as a negative regulator of FceRI-mediated signal transduction leading to cytokine production and degranulation, most likely by acting at the level of SYK to affect downstream events such as phosphorylation of SLP76 and LAT and mobilization of Ca(2+) (By similarity).
Gene ID
19267
Gene Name (Vector)
protein tyrosine phosphatase, receptor type, E
Gene Symbol
Ptpre
ORF Size (aa)
2100
ORF Size (bp)
2100 bp
RefSeq ID
NM_011212
RefSeq Synonyms
NM_011212, NM_001316681, NM_001316680, NM_001316679, NM_001316678, BC160345,
Species
mouse
UniGene ID
Mm.945
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.