mouse POLR3D Adenovirus
This is an Adenovirus expressing Mouse Polr3d.
ADV-269052
Ad-m-POLR3D
Ready-to-use Adenovirus expressing Mouse Polr3d (polymerase (RNA) III (DNA directed) polypeptide D). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
2810426M17Rik; 44kDa; AI326118; AW489084; BN51T; RPC4; TSBN51
Description (Vector)
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF- Kappa-B through the RIG-I pathway (By similarity).
Gene ID
67065
Gene Name (Vector)
polymerase (RNA) III (DNA directed) polypeptide D
Gene Symbol
Polr3d
ORF Size (aa)
1197
ORF Size (bp)
1197 bp
RefSeq ID
NM_025945
RefSeq Synonyms
NM_025945, NM_001164082, BC016102,
Species
mouse
UniGene ID
Mm.20420
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.