mouse POLI Adenovirus
This is an Adenovirus expressing Mouse Poli.
ADV-269018
Ad-m-POLI
Ready-to-use Adenovirus expressing Mouse Poli (polymerase (DNA directed), iota). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Rad30b
Description (Vector)
Error-prone DNA polymerase specifically involved in DNA repair. Plays an important role in translesion synthesis, where the normal high-fidelity DNA polymerases cannot proceed and DNA synthesis stalls. Favors Hoogsteen base-pairing in the active site. Inserts the correct base with high-fidelity opposite an adenosine template. Exhibits low fidelity and efficiency opposite a thymidine template, where it will preferentially insert guanosine. May play a role in hypermutation of immunogobulin genes. Forms a Schiff base with 5'-deoxyribose phosphate at abasic sites, but may not have lyase activity.
Gene ID
26447
Gene Name (Vector)
polymerase (DNA directed), iota
Gene Symbol
Poli
ORF Size (aa)
2025
ORF Size (bp)
2025 bp
RefSeq ID
NM_011972
RefSeq Synonyms
NM_011972, NM_001289516, NM_001289515, NM_001136090, BC082278,
Species
mouse
UniGene ID
Mm.244352
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.