mouse PELP1 Adenovirus
This is an Adenovirus expressing Mouse Pelp1.
ADV-268392
Ad-m-PELP1
Ready-to-use Adenovirus expressing Mouse Pelp1 (proline, glutamic acid and leucine rich protein 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
4930563C04Rik; MNAR
Description (Vector)
Coactivator of estrogen receptor-mediated transcription and a corepressor of other nuclear hormone receptors and sequence-specific transcription factors. Plays a role in estrogen receptor (ER) genomic activity when present in the nuclear compartment by activating the ER target genes in a hormonal stimulation dependent manner. Can facilitate ER non-genomic signaling via SRC and PI3K interaction in the cytosol. Plays a role in E2-mediated cell cycle progression by interacting with RB1. May have important functional implications in ER/growth factor cross-talk. Interacts with several growth factor signaling components including EGFR and HRS. Involved in nuclear receptor signaling via its interaction with AR and NR3C1. May promote tumorigenesis via its interaction with and modulation of several oncogenes including SRC, PI3K, STAT3 and EGFR. Plays a role in cancer cell metastasis via its ability to modulate E2-mediated cytoskeleton changes and cell migration via its interaction with SRC and PI3K.
Gene ID
75273
Gene Name (Vector)
proline, glutamic acid and leucine rich protein 1
Gene Symbol
Pelp1
ORF Size (aa)
3372
ORF Size (bp)
3372 bp
RefSeq ID
NM_029231
RefSeq Synonyms
NM_029231, BC090620, BC016444,
Species
mouse
UniGene ID
Mm.340601
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.