mouse NPHP1 Adenovirus
This is an Adenovirus expressing Mouse Nphp1.
ADV-265982
Ad-m-NPHP1
Ready-to-use Adenovirus expressing Mouse Nphp1 (nephronophthisis 1 (juvenile) homolog (human)). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
Together with BCAR1 it may play a role in the control of epithelial cell polarity. Involved in the organization of apical junctions in kidney cells together with NPHP4 and RPGRIP1L/NPHP8 (By similarity). Does not seem to be strictly required for ciliogenesis (By similarity). Seems to help to recruit PTK2B/PYK2 to cell matrix adhesions, thereby initiating phosphorylation of PTK2B/PYK2 and PTK2B/PYK2-dependent signaling. May play a role in the regulation of intraflagellar transport (IFT) during cilia assembly. Required for normal retina development. In connecting photoreceptor cilia influences the movement of some IFT proteins such as IFT88 and WDR19. Involved in spermatogenesis (By similarity).
Gene ID
53885
Gene Name (Vector)
nephronophthisis 1 (juvenile) homolog (human)
Gene Symbol
Nphp1
ORF Size (aa)
2058
ORF Size (bp)
2058 bp
RefSeq ID
NM_016902
RefSeq Synonyms
NM_016902, NM_001291013, NM_001291012, BC118953,
Species
mouse
UniGene ID
Mm.477771
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.