mouse NOS2 Adenovirus

Name 
Ad-m-NOS2
Cat No 
ADV-265939
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Mouse Nos2.

ADV-265939
Ad-m-NOS2

Ready-to-use Adenovirus expressing Mouse Nos2 (nitric oxide synthase 2, inducible). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
inducible nitric oxide synthase; inducible NO synthase; inducible NOS; iNOS; i-NOS; MAC-NOS; macrophage NOS; nitric oxide synthase 2, inducible, macrophage; nitric oxide synthase, inducible; NOS type II; Nos-2; Nos2a; NOS-II; peptidyl-cysteine S-nitrosylase NOS2
Description (eCommerce)
Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. Nitric oxide synthase is expressed in liver and is inducible by a combination of lipopolysaccharide and certain cytokines. [taken from NCBI Entrez Gene (Gene ID: 4843)].
Description (Vector)
Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such COX2.
Gene ID
18126
Gene Name (eCommerce)
nitric oxide synthase 2, inducible
Gene Name (Vector)
nitric oxide synthase 2, inducible
Gene Symbol
Nos2
NCBI Taxonomy ID (eCommerce)
10090.0
ORF Size (aa)
3438
ORF Size (bp)
3438 bp
Protein Name (eCommerce)
Nitric oxide synthase, inducible
RefSeq ID
NM_010927
RefSeq Synonyms
NM_010927, NM_001313922, NM_001313921, BC062378,
Research Areas
Cancer,Cardiology,Cardiovascular,Cytoskeleton,Gene Expression,HIF-1 Signaling,Hypoxia,IFN Signaling,Immunology,Innate Immunity,Interleukin Signaling,Lung Cancer,Neurobiology,Prolactin Signaling,Signal Transduction
Research Areas (Faceted)
cancer,cardiovascular,cell_biology,immunology,neurobiology,signal_transduction
Species
mouse
Target Sentence
Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. Nitric oxide synthase is expressed in liver and is inducible by a combination of lipopolysaccharide and certain cytokines. [taken from NCBI Entrez Gene (Gene ID: 4843)].
UniGene ID
Mm.2893
UniProt ID (eCommerce)
P29477

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.