mouse NFKBIB Adenovirus

Name 
Ad-m-NFKBIB
Cat No 
ADV-265726
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Mouse Nfkbib.

ADV-265726
Ad-m-NFKBIB

Ready-to-use Adenovirus expressing Mouse Nfkbib (nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, beta). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
I(Kappa)B(beta); I-kappa-B-beta; IKappaBbeta; IkB; ikB-B; IKB-beta; IkBb; NF-kappa-BIB
Description (Vector)
Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further NFKBIA-dependent inactivation. Association with inhibitor kappa B-interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation.
Gene ID
18036
Gene Name (Vector)
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, beta
Gene Symbol
Nfkbib
ORF Size (aa)
1080
ORF Size (bp)
1080 bp
RefSeq ID
NM_010908
RefSeq Synonyms
NM_010908, NM_001306222, BC021938,
Species
mouse
UniGene ID
Mm.220333

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.