mouse NDST1 Adenovirus

Name
Ad-m-NDST1

Cat No
ADV-265553

Availability
4-5 weeks

This is an Adenovirus expressing Mouse Ndst1.

ADV-265553

Ad-m-NDST1

Ready-to-use Adenovirus expressing Mouse Ndst1 (N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

1200015G06Rik; b2b2230Clo; Hsst; NDST-1

Description (Vector)

Essential bifunctional enzyme that catalyzes both the N-deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosaminoglycan in heparan sulfate. Modifies the GlcNAc-GlcA dissacharide repeating sugar backbone to make N-sulfated heparosan, a prerequisite substrate for later modifications in heparin biosynthesis. Plays a role in determining the extent and pattern of sulfation of heparan sulfate. Compared to other NDST enzymes, its presence is absolutely required. Participates in biosynthesis of heparan sulfate that can ultimately serve as L-selectin ligands, thereby playing a role in inflammatory response.

Gene ID

15531

Gene Name (Vector)

N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1

Gene Symbol

Ndst1

ORF Size (aa)

2649

ORF Size (bp)

2649 bp

RefSeq ID

NM_008306

RefSeq Synonyms

NM_008306, BC079561, BC066098,

Species

mouse

UniGene ID

Mm.181862

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.