mouse MYO7A Adenovirus
This is an Adenovirus expressing Mouse Myo7a.
ADV-265342
Ad-m-MYO7A
Ready-to-use Adenovirus expressing Mouse Myo7a (myosin VIIA). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Hdb; Myo7; nmf371; polka; sh-1; sh1; USH1B
Description (Vector)
Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails bind to membranous compartments, which are then moved relative to actin filaments. In the retina, plays an important role in the renewal of the outer photoreceptor disks. Plays an important role in the distribution and migration of retinal pigment epithelial (RPE) melanosomes and phagosomes, and in the regulation of opsin transport in retinal photoreceptors. In the inner ear, plays an important role in differentiation, morphogenesis and organization of cochlear hair cell bundles. Involved in hair-cell vesicle trafficking of aminoglycosides, which are known to induce ototoxicity (By similarity). Motor protein that is a part of the functional network formed by USH1C, USH1G, CDH23 and MYO7A that mediates mechanotransduction in cochlear hair cells. Required for normal hearing.
Gene ID
17921
Gene Name (Vector)
myosin VIIA
Gene Symbol
Myo7a
ORF Size (aa)
6531
ORF Size (bp)
6531 bp
RefSeq ID
NM_008663
RefSeq Synonyms
NM_008663, NM_001256083, NM_001256082, NM_001256081, BC172681, BC156494,
Species
mouse
UniGene ID
Mm.1403
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.