mouse LRDD Adenovirus

Name 
Ad-m-LRDD
Cat No 
ADV-263795
Availability
4-5 weeks

This is an Adenovirus expressing Mouse LRDD.

ADV-263795
Ad-m-LRDD

Ready-to-use Adenovirus expressing Mouse Pidd1 (p53 induced death domain protein 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
1200011D09Rik; AU042446; Lrdd; Pidd
Description (Vector)
Promotes apoptosis downstream of the tumor suppressor as component of the DNA damage/stress response pathway that connects p53/TP53 to apoptosis. Associates with NEMO/IKBKG and RIP1 and enhances sumoylation and ubiquitination of NEMO/IKBKG which is important for activation of the transcription factor NF-kappa-B. Associates with CASP2/caspase-2 and CRADD/RAIDD, and induces activation of CASP2 which an important regulator in apoptotic pathways.
Gene ID
57913
Gene Name (Vector)
p53 induced death domain protein 1
Gene Symbol
Pidd1
ORF Size (aa)
2748
ORF Size (bp)
2748 bp
RefSeq ID
NM_022654
RefSeq Synonyms
NM_022654, BC145857,
Species
mouse
UniGene ID
Mm.334321

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.