mouse KLHL21 Adenovirus

Name
Ad-m-KLHL21

Cat No
ADV-262907

Availability
4-5 weeks

This is an Adenovirus expressing Mouse KLHL21.

ADV-262907

Ad-m-KLHL21

Ready-to-use Adenovirus expressing Mouse Klhl21 (kelch-like 21). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

1810045K06Rik; D330008A20; mKIAA0469

Description (Vector)

Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for efficient chromosome alignment and cytokinesis. The BCR(KLHL21) E3 ubiquitin ligase complex regulates localization of the chromosomal passenger complex (CPC) from chromosomes to the spindle midzone in anaphase and mediates the ubiquitination of AURKB. Ubiquitination of AURKB by BCR(KLHL21) E3 ubiquitin ligase complex may not lead to its degradation by the proteasome.

Gene ID

242785

Gene Name (Vector)

kelch-like 21

Gene Symbol

Klhl21

ORF Size (aa)

1794

ORF Size (bp)

1794 bp

RefSeq ID

NM_001033352

RefSeq Synonyms

NM_001033352, BC141159, BC141158,

Species

mouse

UniGene ID

Mm.22306

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.