mouse HOMER1 Adenovirus
This is an Adenovirus expressing Mouse HOMER1.
ADV-261546
Ad-m-HOMER1
Ready-to-use Adenovirus expressing Mouse Homer1 (homer scaffolding protein 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
homer-1; PSD-Zip45; SYN47; Ves-1; vesl-1
Description (Vector)
Postsynaptic density scaffolding protein. Binds and cross-links cytoplasmic regions of GRM1, GRM5, ITPR1, DNM3, RYR1, RYR2, SHANK1 and SHANK3. By physically linking GRM1 and GRM5 with ER-associated ITPR1 receptors, it aids the coupling of surface receptors to intracellular calcium release. May also couple GRM1 to PI3 kinase through its interaction with AGAP2. Isoform 1 regulates the trafficking and surface expression of GRM5. Isoform 3 acts as a natural dominant negative, in dynamic competition with constitutively expressed isoform 1 to regulate synaptic metabotropic glutamate function. Isoform 3, may be involved in the structural changes that occur at synapses during long-lasting neuronal plasticity and development.
Gene ID
26556
Gene Name (Vector)
homer scaffolding protein 1
Gene Symbol
Homer1
ORF Size (aa)
561
RefSeq ID
NM_152134
RefSeq Synonyms
NM_152134, NM_147176, NM_011982, NM_001347598, NM_001284189, BC064041,
Species
mouse
UniGene ID
Mm.37533
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.