mouse GRIA4 Adenovirus

Name
Ad-m-GRIA4

Cat No
ADV-260754

Availability
4-5 weeks

This is an Adenovirus expressing Mouse GRIA4.

ADV-260754

Ad-m-GRIA4

Ready-to-use Adenovirus expressing Mouse Gria4 (glutamate receptor, ionotropic, AMPA4 (alpha 4)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

GluA4; Glur-4; GluR-D; Glur4; Gluralpha4; spkw1

Description (Vector)

Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist.In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.

Gene ID

14802

Gene Name (Vector)

glutamate receptor, ionotropic, AMPA4 (alpha 4)

Gene Symbol

Gria4

ORF Size (aa)

2709

ORF Size (bp)

2709 bp

RefSeq ID

NM_019691

RefSeq Synonyms

NM_019691, NM_001113181, NM_001113180, BC060697,

Species

mouse

UniGene ID

Mm.477102

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.