mouse FNBP1 Adenovirus
This is an Adenovirus expressing Mouse Fnbp1.
ADV-259520
Ad-m-FNBP1
Ready-to-use Adenovirus expressing Mouse Fnbp1 (formin binding protein 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
1110057E06Rik; 2210010H06Rik; FBP1; Fbp17
Description (Vector)
FNBP1 may act as a link between RND2 signaling and regulation of the actin cytoskeleton (By similarity). Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during the late stage of clathrin-mediated endocytosis. Binds to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promotes membrane invagination and the formation of tubules. Also enhances actin polymerization via the recruitment of WASL/N-WASP, which in turn activates the Arp2/3 complex. Actin polymerization may promote the fission of membrane tubules to form endocytic vesicles. May be required for the lysosomal retention of FASLG/FASL.
Gene ID
14269
Gene Name (Vector)
formin binding protein 1
Gene Symbol
Fnbp1
ORF Size (aa)
1017
ORF Size (bp)
1017 bp
RefSeq ID
NM_019406
RefSeq Synonyms
NM_019406, NM_001177650, NM_001177649, NM_001177648, NM_001038700, BC003867,
Species
mouse
UniGene ID
Mm.440993
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.