Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Mouse

Gene Symbol

Fbxo5

Gene Name

F-box protein 5

Gene ID

67141

Gene Synonyms

2510044I10Rik; C85305; Emi1; Fbxo31

ORF Size

1266 bp

RefSeq#

BC053434

Gene Description

Regulates progression through early mitosis by inhibiting the anaphase promoting complex/cyclosome (APC). Binds to the APC activators CDC20 and FZR1/CDH1 to prevent APC activation. Can also bind directly to the APC to inhibit substrate-binding.

UniGene ID

Mm.197520