mouse EXO1 Adenovirus
This is an Adenovirus expressing Mouse Exo1.
ADV-258767
Ad-m-EXO1
Ready-to-use Adenovirus expressing Mouse Exo1 (exonuclease 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
5730442G03Rik; Msa
Description (Vector)
5'->3' double-stranded DNA exonuclease which may also possess a cryptic 3'->5' double-stranded DNA exonuclease activity. Functions in DNA mismatch repair (MMR) to excise mismatch-containing DNA tracts directed by strand breaks located either 5' or 3' to the mismatch. Also exhibits endonuclease activity against 5'-overhanging flap structures similar to those generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Required for somatic hypermutation (SHM) and class switch recombination (CSR) of immunoglobulin genes. Essential for male and female meiosis.
Gene ID
26909
Gene Name (Vector)
exonuclease 1
Gene Symbol
Exo1
ORF Size (aa)
2514
ORF Size (bp)
2514 bp
RefSeq ID
NM_012012
RefSeq Synonyms
NM_012012, BC006671,
Species
mouse
UniGene ID
Mm.283046
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.