mouse EPHB4 Adenovirus
This is an Adenovirus expressing Mouse EPHB4.
ADV-258582
Ad-m-EPHB4
Ready-to-use Adenovirus expressing Mouse Ephb4 (Eph receptor B4). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AI042935; Htk; MDK2; Myk1; Tyro11
Description (Vector)
Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Together with its cognate ligand/functional ligand EFNB2 plays a central role in heart morphogenesis and angiogenesis through regulation of cell adhesion and cell migration. EPHB4-mediated forward signaling controls cellular repulsion and segregation form EFNB2-expressing cells. Plays also a role in postnatal blood vessel remodeling, morphogenesis and permeability and is thus important in the context of tumor angiogenesis.
Gene ID
13846
Gene Name (Vector)
Eph receptor B4
Gene Symbol
Ephb4
ORF Size (aa)
2964
ORF Size (bp)
2964 bp
RefSeq ID
NM_010144
RefSeq Synonyms
NM_010144, NM_001159571, BC016505,
Species
mouse
UniGene ID
Mm.34533
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.