mouse DNMT1 Adenovirus
This is an Adenovirus expressing Mouse Dnmt1.
ADV-257355
Ad-m-DNMT1
Ready-to-use Adenovirus expressing Mouse Dnmt1 (DNA methyltransferase (cytosine-5) 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Cxxc9; Dnmt; Dnmt1o; m.MmuI; MCMT; Met-1; Met1; MommeD2; MTase
Description (Vector)
Methylates CpG residues. Preferentially methylates hemimethylated DNA. Associates with DNA replication sites in S phase maintaining the methylation pattern in the newly synthesized strand, that is essential for epigenetic inheritance. Associates with chromatin during G2 and M phases to maintain DNA methylation independently of replication. It is responsible for maintaining methylation patterns established in development. DNA methylation is coordinated with methylation of histones. Mediates transcriptional repression by direct binding to HDAC2. In association with DNMT3B and via the recruitment of CTCFL/BORIS, involved in activation of BAG1 gene expression by modulating dimethylation of promoter histone H3 at H3K4 and H3K9.
Gene ID
13433
Gene Name (Vector)
DNA methyltransferase (cytosine-5) 1
Gene Symbol
Dnmt1
ORF Size (aa)
4863
ORF Size (bp)
4863 bp
RefSeq ID
NM_010066
RefSeq Synonyms
NM_010066, NM_001314011, NM_001199433, NM_001199432, NM_001199431, BC053047, BC048148,
Species
mouse
UniGene ID
Mm.128580
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.