mouse CYFIP1 Adenovirus

Name
Ad-m-CYFIP1

Cat No
ADV-256449

Availability
4-5 weeks

This is an Adenovirus expressing Mouse CYFIP1.

ADV-256449

Ad-m-CYFIP1

Ready-to-use Adenovirus expressing Mouse Cyfip1 (cytoplasmic FMR1 interacting protein 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

E030028J09Rik; l(7)1Rl; l71Rl; l7Rl1; mKIAA0068; P140SRA-1; P140sra1; pl-1; Shyc; Sra-1; Sra1

Description (Vector)

Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit is an adapter between EIF4E and FMR1. Promotes the translation repression activity of FMR1 in brain probably by mediating its association with EIF4E and mRNA (By similarity). Regulates formation of membrane ruffles and lamellipodia. Plays a role in axon outgrowth. Binds to F-actin but not to RNA. Part of the WAVE complex that regulates actin filament reorganization via its interaction with the Arp2/3 complex. Actin remodeling activity is regulated by RAC1. Regulator of epithelial morphogenesis. May act as an invasion suppressor in cancers.

Gene ID

20430

Gene Name (Vector)

cytoplasmic FMR1 interacting protein 1

Gene Symbol

Cyfip1

ORF Size (aa)

3756

ORF Size (bp)

3756 bp

RefSeq ID

NM_011370

RefSeq Synonyms

NM_011370, NM_001164662, NM_001164661, BC054429, BC052713, BC047135,

Species

mouse

UniGene ID

Mm.37249

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.