mouse COPS7A Adenovirus

Name
Ad-m-COPS7A

Cat No
ADV-255923

Availability
4-5 weeks

This is an Adenovirus expressing Mouse COPS7A.

ADV-255923

Ad-m-COPS7A

Ready-to-use Adenovirus expressing Mouse Cops7a (COP9 signalosome subunit 7A). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

D6Ertd35e

Description (Vector)

Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, JUN, I-kappa-B-alpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.

Gene ID

26894

Gene Name (Vector)

COP9 signalosome subunit 7A

Gene Symbol

Cops7a

ORF Size (aa)

828

ORF Size (bp)

828 bp

RefSeq ID

NM_012003

RefSeq Synonyms

NM_012003, NM_001164089, BC003724,

Species

mouse

UniGene ID

Mm.439837

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.