mouse CIB1 Adenovirus
This is an Adenovirus expressing Mouse CIB1.
ADV-255495
Ad-m-CIB1
Ready-to-use Adenovirus expressing Mouse Cib1 (calcium and integrin binding 1 (calmyrin)). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Cibkip; Kip; Prkdcip
Description (Vector)
CIB1 may convert the inactive conformation of integrin alpha-IIb/beta3 to an active form through binding to the integrin cytoplasmic domain. Induces cell migration and spreading mediated through integrin (possibly via focal adhesion complexes). Functions as a negative regulator of stress activated MAP kinase (MAPK) signaling pathways. May play a role in regulation of apoptosis. Interacts with and up-regulates PTK2/FAK1 activity. Down regulates inositol 1,4,5-trisphosphate receptor-dependent calcium signaling. Participates in endomitotic cell cycle, a form of mitosis in which both karyokinesis and cytokinesis are interrupted and is a hallmark of megakaryocyte differentiation.
Gene ID
23991
Gene Name (Vector)
calcium and integrin binding 1 (calmyrin)
Gene Symbol
Cib1
ORF Size (aa)
576
ORF Size (bp)
576 bp
RefSeq ID
NM_011870
RefSeq Synonyms
NM_011870, NM_001291276, NM_001291275, BC054385, BC003714,
Species
mouse
UniGene ID
Mm.30217
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.