mouse BBS2 Adenovirus

Name 
Ad-m-BBS2
Cat No 
ADV-253659
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Mouse Bbs2.

ADV-253659
Ad-m-BBS2

Ready-to-use Adenovirus expressing Mouse Bbs2 (Bardet-Biedl syndrome 2 (human)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
2410125H22Rik; AI447581
Description (Vector)
The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the guanosyl exchange factor (GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane.
Gene ID
67378
Gene Name (Vector)
Bardet-Biedl syndrome 2 (human)
Gene Symbol
Bbs2
ORF Size (aa)
2166
ORF Size (bp)
2166 bp
RefSeq ID
NM_026116
RefSeq Synonyms
NM_026116, BC057184,
Species
mouse
UniGene ID
Mm.292107

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.