mouse BAX Adenovirus

Name 
Ad-m-BAX
Cat No 
ADV-253636
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human PCP2.

ADV-253636
Ad-m-BAX

Ready-to-use Adenovirus expressing Mouse Bax (BCL2-associated X protein). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Description (Vector)
Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.
Gene ID
12028
Gene Name (Vector)
BCL2-associated X protein
Gene Symbol
Bax
ORF Size (aa)
579
ORF Size (bp)
579 bp
RefSeq ID
NM_007527
RefSeq Synonyms
NM_007527, BC053380, BC018228,
Species
mouse
UniGene ID
Mm.19904

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.