mouse ASAH2 Adenovirus

Name
Ad-m-ASAH2

Cat No
ADV-253116

Availability
4-5 weeks

This is an Adenovirus expressing Mouse ASAH2.

ADV-253116

Ad-m-ASAH2

Ready-to-use Adenovirus expressing Mouse Asah2 (N-acylsphingosine amidohydrolase 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

AI585898

Description (Vector)

Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid at an optimal pH of 6.5-8.5. Acts as a key regulator of sphingolipid signaling metabolites by generating sphingosine at the cell surface. Acts as a repressor of apoptosis both by reducing C16-ceramide, thereby preventing ceramide-induced apoptosis, and generating sphingosine, a precursor of the antiapoptotic factor sphingosine 1-phosphate. Probably involved in the digestion of dietary sphingolipids in intestine by acting as a key enzyme for the catabolism of dietary sphingolipids and regulating the levels of bioactive sphingolipid metabolites in the intestinal tract.

Gene ID

54447

Gene Name (Vector)

N-acylsphingosine amidohydrolase 2

Gene Symbol

Asah2

ORF Size (aa)

2271

ORF Size (bp)

2271 bp

RefSeq ID

NM_018830

RefSeq Synonyms

NM_018830, BC145016, BC137898,

Species

mouse

UniGene ID

Mm.104900

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.