mouse ARHGEF18 Adenovirus

Name 
Ad-m-ARHGEF18
Cat No 
ADV-252973
Availability
4-5 weeks

This is an Adenovirus expressing Human P2RY1.

ADV-252973
Ad-m-ARHGEF18

Ready-to-use Adenovirus expressing Mouse Arhgef18 (rho/rac guanine nucleotide exchange factor (GEF) 18). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
AI467246; D030053O22Rik
Description (Vector)
Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPases. May play a role in actin cytoskeleton reorganization in different tissues since its activation induces formation of actin stress fibers. Also act as a GEF for RAC1, inducing production of reactive oxygen species (ROS). Does not act as a GEF for CDC42. The G protein beta-gamma (Gbetagamma) subunits of heterotrimeric G proteins act as activators, explaining the integrated effects of LPA and other G-protein coupled receptor agonists on actin stress fiber formation, cell shape change and ROS production.
Gene ID
102098
Gene Name (Vector)
rho/rac guanine nucleotide exchange factor (GEF) 18
Gene Symbol
Arhgef18
ORF Size (aa)
3066
ORF Size (bp)
3066 bp
RefSeq ID
NM_133962
RefSeq Synonyms
NM_133962, BC060639,
Species
mouse
UniGene ID
Mm.170461

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.