human MBTPS2 Adenovirus

Name
Ad-h-MBTPS2

Cat No
ADV-233501

Availability
4-5 weeks

This is an Adenovirus expressing Human MBTPS2.

ADV-233501

Ad-h-MBTPS2

Ready-to-use Adenovirus expressing Human MBTPS2 (membrane bound transcription factor peptidase, site 2). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

BRESEK; IFAP; KFSD; KFSDX; OLMSX; S2P

Description (Vector)

MBTPS2 encodes a intramembrane zinc metalloprotease, which is essential in development. This protease functions in the signal protein activation involved in sterol control of transcription and the ER stress response. Mutations in this gene have been associated with ichthyosis follicularis with atrichia and photophobia (IFAP syndrome); IFAP syndrome has been quantitatively linked to a reduction in cholesterol homeostasis and ER stress response.

Gene ID

51360

Gene Name (Vector)

membrane bound transcription factor peptidase, site 2

Gene Symbol

MBTPS2

HGNC ID

HGNC:15455

ORF Size (aa)

1560

ORF Size (bp)

1560 bp

RefSeq ID

NM_015884

RefSeq Synonyms

NM_015884, BC036465,

Species

human

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.