human ARHGEF5 Adenovirus
This is an Adenovirus expressing Human ARHGEF5.
ADV-231847
Ad-h-ARHGEF5
Ready-to-use Adenovirus expressing Human ARHGEF5 (Rho guanine nucleotide exchange factor 5). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ephexin3; ephexin-3; GEF5; guanine nucleotide regulatory protein TIM; oncogene TIM; P60; p60 TIM; Rho guanine nucleotide exchange factor (GEF) 5; rho guanine nucleotide exchange factor 5; TIM; TIM1; transforming immortalized mammary oncogene
Description (eCommerce)
ARHGEF5, also known as TIM (transforming immortalized mammary), is an oncogene that belongs to the Dbl family of guanine nucleotide exchange factors (GEFs) for Rho GTPases. It is implicated to play a role in proliferative breast disease.
Description (Vector)
Rho GTPases play a fundamental role in numerous cellular processes initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. This protein may be involved in the control of cytoskeletal organization.
Gene ID
7984
Gene Name (eCommerce)
Rho guanine nucleotide exchange factor 5
Gene Name (Vector)
Rho guanine nucleotide exchange factor 5
Gene Symbol
ARHGEF5
HGNC ID
HGNC:13209
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
4794
ORF Size (bp)
4794 bp
Protein Name (eCommerce)
Rho guanine nucleotide exchange factor 5
RefSeq ID
NM_005435
RefSeq Synonyms
NM_005435, BC136661,
Research Areas
Cancer,EGFR Signaling,RAC1 Signaling,Rho Signaling,Signal Transduction
Research Areas (Faceted)
cancer,signal_transduction
Species
human
Target Sentence
ARHGEF5, also known as TIM (transforming immortalized mammary), is an oncogene that belongs to the Dbl family of guanine nucleotide exchange factors (GEFs) for Rho GTPases. It is implicated to play a role in proliferative breast disease.
UniGene ID
Hs.334
UniProt ID (eCommerce)
Q12774
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.