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human RPL26 Adenovirus

Name 
Ad-h-RPL26
Cat No 
ADV-230684
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human RPL26.

ADV-230684
Ad-h-RPL26

Ready-to-use Adenovirus expressing Human RPL26 (ribosomal protein L26). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
60S ribosomal protein L26; DBA11; L26; large ribosomal subunit protein uL24
Description (eCommerce)
RPL26 is a component of the 60S ribosomal subunit. Ribosomes are composed of a small 40S subunit and a large 60S subunit that function to catalyze protein synthesis. RPL26 is a cytoplasmic protein that functions at the translational level to induce protein expression. RPL26 has been demonstrated to bind the 5’ UTR of p53 mRNA in response to DNA damage. This interaction is described as one of many mechanisms that serve to increase p53 protein levels after DNA damage.
Description (Vector)
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L24P family of ribosomal proteins. It is located in the cytoplasm. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
Gene ID
6154
Gene Name (eCommerce)
ribosomal protein L26
Gene Name (Vector)
ribosomal protein L26
Gene Symbol
RPL26
HGNC ID
HGNC:10327
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
438
Protein Name (eCommerce)
60S ribosomal protein L26
RefSeq ID
NM_000987
RefSeq Synonyms
NM_001315531, NM_001315530, NM_000987, BC071664,
Research Areas
Gene Expression,Host-Virus Interactions,Metabolism/Metabolic Process,RNA Binding,RNA Processing,Translational Control
Research Areas (Faceted)
cell_biology,genetics,infectious_disease,metabolism,transcription_translation
Species
human
Target Sentence
RPL26 is a component of the 60S ribosomal subunit. Ribosomes are composed of a small 40S subunit and a large 60S subunit that function to catalyze protein synthesis. RPL26 is a cytoplasmic protein that functions at the translational level to induce protein expression. RPL26 has been demonstrated to bind the 5’ UTR of p53 mRNA in response to DNA damage. This interaction is described as one of many mechanisms that serve to increase p53 protein levels after DNA damage.
UniGene ID
Hs.644794
UniProt ID (eCommerce)
P61254

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.