human SLC9A3R1 Adenovirus

Name
Ad-h-SLC9A3R1

Cat No
ADV-229920

Availability
4-5 weeks

This is an Adenovirus expressing Human SLC9A3R1.

ADV-229920

Ad-h-SLC9A3R1

Ready-to-use Adenovirus expressing Human SLC9A3R1 (SLC9A3 regulator 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

EBP50; ezrin-radixin-moesin binding phosphoprotein-50; Ezrin-radixin-moesin-binding phosphoprotein 50; Na(+)/H(+) exchange regulatory cofactor NHE-RF1; Na+/H+ exchange regulatory co-factor; NHERF; NHERF1; NHERF-1; NPHLOP2; regulatory cofactor of Na(+)/H(+) exchanger; Sodium-hydrogen exchanger regulatory factor 1; solute carrier family 9 (sodium/hydrogen exchanger), isoform 3 regulatory factor 1; solute carrier family 9 isoform A3 regulatory factor 1; solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1

Description (eCommerce)

NHERF1 (sodium-hydrogen exchanger regulatory factor 1) is a sodium/hydrogen exchanger regulatory cofactor. The protein interacts with and regulates various proteins including the cystic fibrosis transmembrane conductance regulator and G-protein coupled receptors such as the beta2-adrenergic receptor and the parathyroid hormone 1 receptor. The protein also interacts with proteins that function as linkers between integral membrane and cytoskeletal proteins. The protein localizes to actin-rich structures including membrane ruffles, microvilli, and filopodia. Mutations in this gene result in hypophosphatemic nephrolithiasis/osteoporosis type 2, and loss of heterozygosity of this gene is implicated in breast cancer [taken from NCBI Entrez Gene (Gene ID: 9368)].

Description (Vector)

SLC9A3R1 encodes a sodium/hydrogen exchanger regulatory cofactor. The protein interacts with and regulates various proteins including the cystic fibrosis transmembrane conductance regulator and G-protein coupled receptors such as the beta2-adrenergic receptor and the parathyroid hormone 1 receptor. The protein also interacts with proteins that function as linkers between integral membrane and cytoskeletal proteins. The protein localizes to actin-rich structures including membrane ruffles, microvilli, and filopodia. Mutations in this gene result in hypophosphatemic nephrolithiasis/osteoporosis type 2, and loss of heterozygosity of this gene is implicated in breast cancer.

Gene ID

9368

Gene Name (eCommerce)

SLC9A3 regulator 1

Gene Name (Vector)

SLC9A3 regulator 1

Gene Symbol

SLC9A3R1

HGNC ID

HGNC:11075

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

1077

Protein Name (eCommerce)

Na(+)/H(+) exchange regulatory cofactor NHE-RF1

RefSeq ID

NM_004252

RefSeq Synonyms

NM_004252, BC053350, BC011777, BC003361, BC001443,

Research Areas

Apoptosis,Cytoskeleton,Neurobiology,PDGF Signaling,Signal Transduction,Transport,Wnt Signaling

Research Areas (Faceted)

cell_biology,neurobiology,signal_transduction

Species

human

Target Sentence

UniGene ID

Hs.711846

UniProt ID (eCommerce)

O14745

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.