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human ZNF423 Adenovirus

Name 
Ad-h-ZNF423
Cat No 
ADV-228554
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human ZNF423.

ADV-228554
Ad-h-ZNF423

Ready-to-use Adenovirus expressing Human ZNF423 (zinc finger protein 423). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
early B-cell factor associated zinc finger protein; Ebfa; ZhOA; ZJBTS19; NPHP14; OA; ZOLF-1/EBF associated zinc finger; olf1/EBF-associated zinc finger protein; Roa; ZSmad- and Olf-interacting zinc finger protein; Zfp104; ZFP423; zinc finger protein 423
Description (eCommerce)
Olf1/EBF-associated zinc finger protein (OAZ) is a transcription factor that can act as either an activator or a repressor depending on the context. OAZ plays a central role in BMP signaling and olfactory neurogenesis. It associates with SMADs in response to BMP2 leading to activate transcription of BMP target genes. OAZ also acts as a transcriptional repressor via its interaction with EBF1, a transcription factor involved in terminal olfactory receptor neurons differentiation. OAZ is involved in olfactory neurogenesis by participating in a developmental switch that regulates the transition from differentiation to maturation in olfactory receptor neurons. Additionally, OAZ controls proliferation and differentiation of neural precursors in cerebellar vermis formation [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q2M1K9].
Description (Vector)
ZNF423 is a nuclear protein that belongs to the family of Kruppel-like C2H2 zinc finger proteins. It functions as a DNA-binding transcription factor by using distinct zinc fingers in different signaling pathways. Thus, it is thought that this gene may have multiple roles in signal transduction during development.
Gene ID
23090
Gene Name (eCommerce)
zinc finger protein 423
Gene Name (Vector)
zinc finger protein 423
Gene Symbol
ZNF423
HGNC ID
HGNC:16762
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
3855
ORF Size (bp)
3855 bp
Protein Name (eCommerce)
Zinc finger protein 423
RefSeq ID
NM_015069
RefSeq Synonyms
NM_015069, NM_001330533, NM_001271620, BC112317, BC112315,
Research Areas
Neurobiology,Neurodevelopment,Neurogenesis,Notch Signaling,Signal Transduction,TGF-beta Signaling,Transcription Factor/Regulator,Zinc-finger
Research Areas (Faceted)
cell_biology,developmental_biology,immunology,neurobiology,signal_transduction,transcription_translation
Species
human
Target Sentence
Olf1/EBF-associated zinc finger protein (OAZ) is a transcription factor that can act as either an activator or a repressor depending on the context. OAZ plays a central role in BMP signaling and olfactory neurogenesis. It associates with SMADs in response to BMP2 leading to activate transcription of BMP target genes. OAZ also acts as a transcriptional repressor via its interaction with EBF1, a transcription factor involved in terminal olfactory receptor neurons differentiation. OAZ is involved in olfactory neurogenesis by participating in a developmental switch that regulates the transition from differentiation to maturation in olfactory receptor neurons. Additionally, OAZ controls proliferation and differentiation of neural precursors in cerebellar vermis formation [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q2M1K9].
UniGene ID
Hs.530930
UniProt ID (eCommerce)
Q2M1K9

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.