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human WTAP Adenovirus

Name 
Ad-h-WTAP
Cat No 
ADV-227851
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human WTAP.

ADV-227851
Ad-h-WTAP

Ready-to-use Adenovirus expressing Human WTAP (Wilms tumor 1 associated protein). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
female-lethal(2)D homolog; hFL(2)D; Mum2; PNAS-132; pre-mRNA-splicing regulator WTAP; putative pre-mRNA splicing regulator female-lethal(2D); Wilms tumor 1 associated protein; wilms tumor 1-associating protein; Wilms' tumour 1-associating protein; WT1-associated protein
Description (eCommerce)
Wilms’ tumor 1 associated protein (WTAP) is a protein found to associate with the Wilms’ tumor suppressor (WT1). WTAP appears to play a role in cell proliferation and regulation of the G2/M transition. WTAP has been suggested to influence these processes via a function in mRNA stabilization and mRNA splicing.
Description (Vector)
The Wilms tumor suppressor gene WT1 appears to play a role in both transcriptional and posttranscriptional regulation of certain cellular genes. This gene encodes a WT1-associating protein, which is a ubiquitously expressed nuclear protein. Like WT1 protein, this protein is localized throughout the nucleoplasm as well as in speckles and partially colocalizes with splicing factors. Alternative splicing of this gene results in several transcript variants encoding three different isoforms.
Gene ID
9589
Gene Name (eCommerce)
WT1 associated protein
Gene Name (Vector)
Wilms tumor 1 associated protein
Gene Symbol
WTAP
HGNC ID
HGNC:16846
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1191
Protein Name (eCommerce)
Pre-mRNA-splicing regulator WTAP
RefSeq ID
NM_004906
RefSeq Synonyms
NM_152858, NM_152857, NM_004906, NM_001270533, NM_001270532, NM_001270531, BC069192, BC000383,
Research Areas
Apoptosis,Cell Cycle,mRNA Processing,mRNA Splicing,RNA Processing
Research Areas (Faceted)
cell_biology,cell_cycle,genetics,transcription_translation
Species
human
Target Sentence
Wilms’ tumor 1 associated protein (WTAP) is a protein found to associate with the Wilms’ tumor suppressor (WT1). WTAP appears to play a role in cell proliferation and regulation of the G2/M transition. WTAP has been suggested to influence these processes via a function in mRNA stabilization and mRNA splicing.
UniGene ID
Hs.710715
UniProt ID (eCommerce)
Q15007

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.