human UNC13D Adenovirus
This is an Adenovirus expressing Human UNC13D.
ADV-227185
Ad-h-UNC13D
Ready-to-use Adenovirus expressing Human UNC13D (unc-13 homolog D). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
FHL3; HLH3; HPLH3; Munc13-4
Description (Vector)
UNC13D encodes a protein that is a member of the UNC13 family, containing similar domain structure as other family members but lacking an N-terminal phorbol ester-binding C1 domain present in other Munc13 proteins. The protein appears to play a role in vesicle maturation during exocytosis and is involved in regulation of cytolytic granules secretion. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis type 3, a genetically heterogeneous, rare autosomal recessive disorder.
Gene ID
201294
Gene Name (Vector)
unc-13 homolog D
Gene Symbol
UNC13D
HGNC ID
HGNC:23147
ORF Size (aa)
3273
ORF Size (bp)
3273 bp
RefSeq ID
NM_199242
RefSeq Synonyms
NM_199242, BC067084,
Species
human
UniGene ID
Hs.41045
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.