human UCP1 Adenovirus
This is an Adenovirus expressing Human UCP1.
ADV-227119
Ad-h-UCP1
Ready-to-use Adenovirus expressing Human UCP1 (uncoupling protein 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
SLC25A7; UCP
Description (Vector)
Mitochondrial uncoupling proteins (UCP) are members of the family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. This gene is expressed only in brown adipose tissue, a specialized tissue which functions to produce heat.
Gene ID
7350
Gene Name (Vector)
uncoupling protein 1
Gene Symbol
UCP1
HGNC ID
HGNC:12517
ORF Size (aa)
924
ORF Size (bp)
924 bp
RefSeq ID
NM_021833
RefSeq Synonyms
NM_021833, BC098352, BC098258, BC098168, BC096736,
Species
human
UniGene ID
Hs.249211
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.