human UBA7 Adenovirus
This is an Adenovirus expressing Human UBA7.
ADV-226968
Ad-h-UBA7
Ready-to-use Adenovirus expressing Human UBA7 (ubiquitin like modifier activating enzyme 7). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
D8; UBA1B; UBE1L; UBE2
Description (Vector)
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme is a retinoid target that triggers promyelocytic leukemia (PML)/retinoic acid receptor alpha (RARalpha) degradation and apoptosis in acute promyelocytic leukemia, where it is involved in the conjugation of the ubiquitin-like interferon-stimulated gene 15 protein.
Gene ID
7318
Gene Name (Vector)
ubiquitin like modifier activating enzyme 7
Gene Symbol
UBA7
HGNC ID
HGNC:12471
ORF Size (aa)
3039
ORF Size (bp)
3039 bp
RefSeq ID
NM_003335
RefSeq Synonyms
NM_003335, BC006378,
Species
human
UniGene ID
Hs.16695
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.