human UBA52 Adenovirus
This is an Adenovirus expressing Human UBA52.
ADV-226963
Ad-h-UBA52
Ready-to-use Adenovirus expressing Human UBA52 (ubiquitin A-52 residue ribosomal protein fusion product 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CEP52; HUBCEP52; L40; RPL40; Ubiquitin A-52 residue ribosomal protein fusion product 1; ubiquitin carboxyl extension protein 52; ubiquitin-52 amino acid fusion protein; ubiquitin-60S ribosomal protein L40; ubiquitin-CEP52
Description (eCommerce)
Ubiquitin (Ub) is a small 76aa highly conserved protein found ubiquitously in eukaryotic organisms. The conjugation of ubiquitin to proteins provides an important means to regulate protein abundance and activity by tagging them for degradation. Ubiquitination is a highly regulated and reversible process that appears to be involved in the regulation of many cellular processes and a variety of clinical disorders.
Description (Vector)
Ubiquitin is a highly conserved nuclear and cytoplasmic protein that has a major role in targeting cellular proteins for degradation by the 26S proteosome. It is also involved in the maintenance of chromatin structure, the regulation of gene expression, and the stress response. Ubiquitin is synthesized as a precursor protein consisting of either polyubiquitin chains or a single ubiquitin moiety fused to an unrelated protein. This gene encodes a fusion protein consisting of ubiquitin at the N terminus and ribosomal protein L40 at the C terminus, a C-terminal extension protein (CEP). Multiple processed pseudogenes derived from this gene are present in the genome.
Gene ID
7311
Gene Name (eCommerce)
ubiquitin A-52 residue ribosomal protein fusion product 1
Gene Name (Vector)
ubiquitin A-52 residue ribosomal protein fusion product 1
Gene Symbol
UBA52
HGNC ID
HGNC:12458
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
387
Protein Name (eCommerce)
Ubiquitin-60S ribosomal protein L40
RefSeq ID
NM_003333
RefSeq Synonyms
NM_003333, NM_001321022, NM_001321021, NM_001321020, NM_001321019, NM_001321018, NM_001321017, NM_001033930, BC143668, BC101832, BC101830,
Research Areas
Antigen Processing and Presentation,Apoptosis,Cancer,Cell Cycle,Complexome,DNA Damage/Repair,DNA Replication,EGFR Signaling,EGFR Signaling in Cancer,Fanconi anemia,FGF Signaling,Gene Expression,Host-Virus Interactions,Hypoxia,Immunology,Innate Immunity,MAPK Signaling,Metabolism/Metabolic Process,Neurobiology,NF-kB Signaling,NGF Signaling,Notch Signaling,Proteasome,RNA Processing,Signal Transduction,T-cell Receptor Signaling,TGF-beta Signaling,Toll-like Receptor Signaling,Transcription Factor/Regulator,Translational Control,Wnt Signaling
Research Areas (Faceted)
cancer,cell_biology,cell_cycle,developmental_biology,genetics,immunology,infectious_disease,metabolism,neurobiology,signal_transduction,transcription_translation
Species
human
Target Sentence
Ubiquitin (Ub) is a small 76aa highly conserved protein found ubiquitously in eukaryotic organisms. The conjugation of ubiquitin to proteins provides an important means to regulate protein abundance and activity by tagging them for degradation. Ubiquitination is a highly regulated and reversible process that appears to be involved in the regulation of many cellular processes and a variety of clinical disorders.
UniGene ID
Hs.5308
UniProt ID (eCommerce)
P62987
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.