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human TRPS1 Adenovirus

Name 
Ad-h-TRPS1
Cat No 
ADV-226559
Availability
4-5 weeks

This is an Adenovirus expressing Human TRPS1.

ADV-226559
Ad-h-TRPS1

Ready-to-use Adenovirus expressing Human TRPS1 (transcriptional repressor GATA binding 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
GC79; LGCR; trichorhinophalangeal syndrome I; tricho-rhino-phalangeal syndrome type I protein; zinc finger protein GC79; zinc finger transcription factor Trps1
Description (eCommerce)
Tricho-rhino-phalangeal syndrome type I protein (TRPS1) is a transcription factor that represses GATA-regulated genes and binds to a dynein light chain protein. Binding of TRPS1 to the dynein light chain protein affects binding to GATA consensus sequences and suppresses its transcriptional activity. Defects in the TRPS1 gene are a cause of tricho-rhino-phalangeal syndrome (TRPS) types I-III [taken from NCBI Entrez Gene (Gene ID: 7227)].
Description (Vector)
TRPS1 encodes a transcription factor that represses GATA-regulated genes and binds to a dynein light chain protein. Binding of the encoded protein to the dynein light chain protein affects binding to GATA consensus sequences and suppresses its transcriptional activity. Defects in this gene are a cause of tricho-rhino-phalangeal syndrome (TRPS) types I-III.
Gene ID
7227
Gene Name (eCommerce)
transcriptional repressor GATA binding 1
Gene Name (Vector)
transcriptional repressor GATA binding 1
Gene Symbol
TRPS1
HGNC ID
HGNC:12340
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2562
ORF Size (bp)
2562 bp
Protein Name (eCommerce)
Zinc finger transcription factor Trps1
RefSeq ID
NM_014112
RefSeq Synonyms
NM_014112, NM_001330599, NM_001282903, NM_001282902, BC125020,
Research Areas
Transcription Factor/Regulator,Zinc-finger
Research Areas (Faceted)
cell_biology,transcription_translation
Species
human
Target Sentence
Tricho-rhino-phalangeal syndrome type I protein (TRPS1) is a transcription factor that represses GATA-regulated genes and binds to a dynein light chain protein. Binding of TRPS1 to the dynein light chain protein affects binding to GATA consensus sequences and suppresses its transcriptional activity. Defects in the TRPS1 gene are a cause of tricho-rhino-phalangeal syndrome (TRPS) types I-III [taken from NCBI Entrez Gene (Gene ID: 7227)].
UniGene ID
Hs.657018
UniProt ID (eCommerce)
Q9UHF7

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.