human THRB Adenovirus
This is an Adenovirus expressing Human CERS5.
ADV-225470
Ad-h-THRB
Ready-to-use Adenovirus expressing Human THRB (thyroid hormone receptor beta). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
C-ERBA-2; C-ERBA-BETA; ERBA2; GRTH; NR1A2; PRTH; THR1; THRB1; THRB2
Description (Vector)
THRB is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Mutations in this gene are known to be a cause of generalized thyroid hormone resistance (GTHR), a syndrome characterized by goiter and high levels of circulating thyroid hormone (T3-T4), with normal or slightly elevated thyroid stimulating hormone (TSH). Several alternatively spliced transcript variants encoding the same protein have been observed for this gene.
Gene ID
7068
Gene Name (Vector)
thyroid hormone receptor beta
Gene Symbol
THRB
HGNC ID
HGNC:11799
ORF Size (aa)
1386
ORF Size (bp)
1386 bp
RefSeq ID
NM_000461
RefSeq Synonyms
NM_001252634, NM_001128177, NM_001128176, NM_000461, BC106930, BC106929,
Species
human
UniGene ID
Hs.187861
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.