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human THOC3 Adenovirus

Name 
Ad-h-THOC3
Cat No 
ADV-225450
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human THOC3.

ADV-225450
Ad-h-THOC3

Ready-to-use Adenovirus expressing Human THOC3 (THO complex 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
hTREX45; TEX1 homolog; THO complex subunit 3; THO3
Description (eCommerce)
THO complex subunit 3 (THOC3) is a component of the nuclear THO transcription elongation complex, which is part of the larger transcription export (TREX) complex that couples messenger RNA processing and export. In humans, the transcription export complex is recruited to the 5'-end of messenger RNAs in a splicing- and cap-dependent manner. Studies of a related complex in mouse suggest that the metazoan transcription export complex is involved in cell differentiation and developmen [taken from NCBI Entrez Gene (Gene ID: 84321)].
Description (Vector)
TEX1 is part of the TREX (transcription/export) complex, which includes THO2 (MIM 300395), HPR1 (MIM 606930), ALY (MIM 604171), and UAP56 (MIM 142560).(supplied by OMIM, Nov 2010)
Gene ID
84321
Gene Name (eCommerce)
THO complex 3
Gene Name (Vector)
THO complex 3
Gene Symbol
THOC3
HGNC ID
HGNC:19072
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
984
Protein Name (eCommerce)
THO complex subunit 3
RefSeq ID
NM_032361
RefSeq Synonyms
NM_032361, BC068499, BC066325, BC006849,
Research Areas
Gene Expression,Host-Virus Interactions,mRNA Processing,mRNA Splicing,mRNA transport,RNA Binding,RNA Processing,RNA Transport
Research Areas (Faceted)
genetics,transcription_translation,infectious_disease,cell_biology
Species
human
Target Sentence
THO complex subunit 3 (THOC3) is a component of the nuclear THO transcription elongation complex, which is part of the larger transcription export (TREX) complex that couples messenger RNA processing and export. In humans, the transcription export complex is recruited to the 5'-end of messenger RNAs in a splicing- and cap-dependent manner. Studies of a related complex in mouse suggest that the metazoan transcription export complex is involved in cell differentiation and developmen [taken from NCBI Entrez Gene (Gene ID: 84321)].
UniGene ID
Hs.715943
UniProt ID (eCommerce)
Q96J01

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.