human TGFBI Adenovirus

Name
Ad-h-TGFBI

Cat No
ADV-225388

Availability
4-5 weeks

This is an Adenovirus expressing Human TGFBI.

ADV-225388

Ad-h-TGFBI

Ready-to-use Adenovirus expressing Human TGFBI (transforming growth factor beta induced). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

BIGH3; CDB1; CDG2; CDGG1; CSD; CSD1; CSD2; CSD3; EBMD; LCD1

Description (Vector)

TGFBI encodes an RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins. This protein plays a role in cell-collagen interactions and may be involved in endochondrial bone formation in cartilage. The protein is induced by transforming growth factor-beta and acts to inhibit cell adhesion. Mutations in this gene are associated with multiple types of corneal dystrophy.

Gene ID

7045

Gene Name (Vector)

transforming growth factor beta induced

Gene Symbol

TGFBI

HGNC ID

HGNC:11771

ORF Size (aa)

2052

ORF Size (bp)

2052 bp

RefSeq ID

NM_000358

RefSeq Synonyms

NM_000358, BC004972, BC000097,

Species

human

UniGene ID

Hs.369397

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.