human TCF3 Adenovirus
This is an Adenovirus expressing Human TCF3.
ADV-225217
Ad-h-TCF3
Ready-to-use Adenovirus expressing Human TCF3 (transcription factor 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AGM8; bHLHb21; E2A; E47; ITF1; TCF-3; VDIR
Description (Vector)
TCF3 encodes a member of the E protein (class I) family of helix-loop-helix transcription factors. E proteins activate transcription by binding to regulatory E-box sequences on target genes as heterodimers or homodimers, and are inhibited by heterodimerization with inhibitor of DNA-binding (class IV) helix-loop-helix proteins. E proteins play a critical role in lymphopoiesis, and the encoded protein is required for B and T lymphocyte development. Deletion of this gene or diminished activity of the encoded protein may play a role in lymphoid malignancies. TCF3 is also involved in several chromosomal translocations that are associated with lymphoid malignancies including pre-B-cell acute lymphoblastic leukemia (t(1;19), with PBX1), childhood leukemia (t(19;19), with TFPT) and acute leukemia (t(12;19), with ZNF384). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 9.
Gene ID
6929
Gene Name (Vector)
transcription factor 3
Gene Symbol
TCF3
HGNC ID
HGNC:11633
ORF Size (aa)
1956
ORF Size (bp)
1956 bp
RefSeq ID
NM_003200
RefSeq Synonyms
NM_003200, NM_001136139, BC110580, BC110579,
Species
human
UniGene ID
Hs.371282
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.