human SYNJ2 Adenovirus

Name
Ad-h-SYNJ2

Cat No
ADV-224820

Availability
4-5 weeks

This is an Adenovirus expressing Human SYNJ2.

ADV-224820

Ad-h-SYNJ2

Ready-to-use Adenovirus expressing Human SYNJ2 (synaptojanin 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

inositol phosphate 5'-phosphatase 2; inositol polyphosphate-5-phosphatase H; INPP5H; phosphoinositide 5-phosphatase; synaptic inositol 1,4,5-trisphosphate 5-phosphatase 2; synaptojanin-2

Description (eCommerce)

Synaptojanin 2 is a member of the inositol-polyphosphate 5-phosphatase family. Synaptojanin 2 interacts with the ras-related C3 botulinum toxin substrate 1, which causes translocation of the encoded protein to the plasma membrane where it inhibits clathrin-mediated endocytosis [taken from NCBI Entrez Gene (Gene ID: 4141)].

Description (Vector)

The gene is a member of the inositol-polyphosphate 5-phosphatase family. The encoded protein interacts with the ras-related C3 botulinum toxin substrate 1, which causes translocation of the encoded protein to the plasma membrane where it inhibits clathrin-mediated endocytosis. Alternative splicing results in multiple transcript variants.

Gene ID

8871

Gene Name (eCommerce)

synaptojanin 2

Gene Name (Vector)

synaptojanin 2

Gene Symbol

SYNJ2

HGNC ID

HGNC:11504

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

2520

ORF Size (bp)

2520 bp

Protein Name (eCommerce)

Synaptojanin-2

RefSeq ID

NM_003898

RefSeq Synonyms

NM_003898, NM_001178088, BC043277,

Research Areas

Brain Development,Kinase/Phosphatase,Metabolism/Metabolic Process,Neurobiology,Neurodevelopment,RNA Binding

Research Areas (Faceted)

cell_biology,developmental_biology,metabolism,neurobiology,signal_transduction

Species

human

Target Sentence

Synaptojanin 2 is a member of the inositol-polyphosphate 5-phosphatase family. Synaptojanin 2 interacts with the ras-related C3 botulinum toxin substrate 1, which causes translocation of the encoded protein to the plasma membrane where it inhibits clathrin-mediated endocytosis [taken from NCBI Entrez Gene (Gene ID: 4141)].

UniGene ID

Hs.434494

UniProt ID (eCommerce)

O15056

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.