human SPTBN1 Adenovirus

Name
Ad-h-SPTBN1

Cat No
ADV-224291

Availability
4-5 weeks

This is an Adenovirus expressing Human SPTBN1.

ADV-224291

Ad-h-SPTBN1

Ready-to-use Adenovirus expressing Human SPTBN1 (spectrin beta, non-erythrocytic 1). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

beta-fodrin; beta-G spectrin; beta-II spectrin; beta-spectrin 2; beta-spectrin II; beta-spectrin non-erythrocytic 1; betaSpII; ELF; embryonic liver beta-fodrin; epididymis luminal protein 102; fodrin beta chain; HEL102; spectrin beta chain, brain 1; spectrin beta chain, non-erythrocytic 1; spectrin, non-erythroid beta chain 1; SPTB2

Description (eCommerce)

Beta spectrin (SPTBN1) is a subunit of the spectrin cytoskeletal scaffolding protein that links the plasma membrane to cytoskeletal actin and functions in cellular shape and organelle organization.

Description (Vector)

Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. It is composed of two antiparallel dimers of alpha- and beta- subunits. This gene is one member of a family of beta-spectrin genes. The encoded protein contains an N-terminal actin-binding domain, and 17 spectrin repeats which are involved in dimer formation. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene ID

6711

Gene Name (eCommerce)

spectrin beta, non-erythrocytic 1

Gene Name (Vector)

spectrin beta, non-erythrocytic 1

Gene Symbol

SPTBN1

HGNC ID

HGNC:11275

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

6468

ORF Size (bp)

6468 bp

Protein Name (eCommerce)

Spectrin beta chain, non-erythrocytic 1

RefSeq ID

NM_003128

RefSeq Synonyms

NM_178313, NM_003128, BC137283, BC137282,

Research Areas

Axon Guidance,Cell Cycle,Cytoskeleton,Golgi Apparatus,Neurobiology,Signal Transduction,TGF-beta Signaling

Research Areas (Faceted)

cell_biology,cell_cycle,genetics,immunology,neurobiology,signal_transduction

Species

human

Target Sentence

Beta spectrin (SPTBN1) is a subunit of the spectrin cytoskeletal scaffolding protein that links the plasma membrane to cytoskeletal actin and functions in cellular shape and organelle organization.

UniGene ID

Hs.705692

UniProt ID (eCommerce)

Q01082

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.