human SPG11 Adenovirus

Name
Ad-h-SPG11

Cat No
ADV-224160

Availability
4-5 weeks

This is an Adenovirus expressing Human SPG11.

ADV-224160

Ad-h-SPG11

Ready-to-use Adenovirus expressing Human SPG11 (spastic paraplegia 11 (autosomal recessive)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

ALS5; CMT2X; KIAA1840

Description (Vector)

SPG11 is a potential transmembrane protein that is phosphorylated upon DNA damage. Defects in this gene are a cause of spastic paraplegia type 11 (SPG11). Multiple transcript variants encoding different isoforms have been found for this gene.

Gene ID

80208

Gene Name (Vector)

spastic paraplegia 11 (autosomal recessive)

Gene Symbol

SPG11

HGNC ID

HGNC:11226

ORF Size (aa)

6993

ORF Size (bp)

6993 bp

RefSeq ID

NM_025137

RefSeq Synonyms

NM_025137, NM_001160227, BC153879, BC150640, BC047416,

Species

human

UniGene ID

Hs.683876

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.