human SPDEF Adenovirus

Name
Ad-h-SPDEF

Cat No
ADV-224142

Availability
4-5 weeks

This is an Adenovirus expressing Human SPDEF.

ADV-224142

Ad-h-SPDEF

Ready-to-use Adenovirus expressing Human SPDEF (SAM pointed domain containing ETS transcription factor). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

bA375E1.3; PDEF

Description (Vector)

SPDEF belongs to the ETS family of transcription factors. It is highly expressed in the prostate epithelial cells, and functions as an androgen-independent transactivator of prostate-specific antigen (PSA) promoter. Higher expression of this protein has also been reported in brain, breast, lung and ovarian tumors, compared to the corresponding normal tissues, and it shows better tumor-association than other cancer-associated molecules, making it a more suitable target for developing specific cancer therapies. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene ID

25803

Gene Name (Vector)

SAM pointed domain containing ETS transcription factor

Gene Symbol

SPDEF

HGNC ID

HGNC:17257

ORF Size (aa)

1008

RefSeq ID

NM_012391

RefSeq Synonyms

NM_012391, NM_001252294, BC021299,

Species

human

UniGene ID

Hs.485158

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.