human SLC6A5 Adenovirus

Name
Ad-h-SLC6A5

Cat No
ADV-223571

Availability
4-5 weeks

This is an Adenovirus expressing Human SLC6A5.

ADV-223571

Ad-h-SLC6A5

Ready-to-use Adenovirus expressing Human SLC6A5 (solute carrier family 6 member 5). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

GLYT-2; GLYT2; HKPX3; NET1

Description (Vector)

SLC6A5 encodes a sodium- and chloride-dependent glycine neurotransmitter transporter. This integral membrane glycoprotein is responsible for the clearance of extracellular glycine during glycine-mediated neurotransmission. This protein is found in glycinergic axons and maintains a high presynaptic pool of neurotransmitter at glycinergic synapses. Mutations in this gene cause hyperekplexia; a heterogenous neurological disorder characterized by exaggerated startle responses and neonatal apnea.

Gene ID

9152

Gene Name (Vector)

solute carrier family 6 member 5

Gene Symbol

SLC6A5

HGNC ID

HGNC:11051

ORF Size (aa)

2394

ORF Size (bp)

2394 bp

RefSeq ID

NM_004211

RefSeq Synonyms

NM_004211, NM_001318369, BC096321, BC096320, BC096319,

Species

human

UniGene ID

Hs.136557

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.