human SLC22A18 Adenovirus
This is an Adenovirus expressing Human SLC22A18.
ADV-223187
Ad-h-SLC22A18
Ready-to-use Adenovirus expressing Human SLC22A18 (solute carrier family 22 member 18). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
BWR1A; BWSCR1A; HET; IMPT1; ITM; ORCTL2; p45-BWR1A; SLC22A1L; TSSC5
Description (Vector)
SLC22A18 is one of several tumor-suppressing subtransferable fragments located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. SLC22A18 is imprinted, with preferential expression from the maternal allele. Mutations in this gene have been found in Wilms' tumor and lung cancer. This protein may act as a transporter of organic cations, and have a role in the transport of chloroquine and quinidine-related compounds in kidney. Two alternatively spliced transcript variants encoding the same protein have been described.
Gene ID
5002
Gene Name (Vector)
solute carrier family 22 member 18
Gene Symbol
SLC22A18
HGNC ID
HGNC:10964
ORF Size (aa)
1275
ORF Size (bp)
1275 bp
RefSeq ID
NM_002555
RefSeq Synonyms
NM_183233, NM_002555, NM_001315502, NM_001315501, BC015571,
Species
human
UniGene ID
Hs.50868
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.