human SENP1 Adenovirus

Name 
Ad-h-SENP1
Cat No 
ADV-222573
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human IL1A.

ADV-222573
Ad-h-SENP1

Ready-to-use Adenovirus expressing Human SENP1 (SUMO1/sentrin specific peptidase 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
sentrin/SUMO-specific protease SENP1; sentrin-specific protease 1; SUMO1/sentrin specific peptidase 1; SUMO1/sentrin specific protease 1; SuPr-2
Description (eCommerce)
SENP1 (sentrin-specific protease) functions as a protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. Deconjugation of SUMO1 from HDAC1 decreases its transcriptional repression activity. SENP1 also deconjugates SUMO1 from HIPK2 [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q9P0U3].
Description (Vector)
SENP1 encodes a cysteine protease that specifically targets members of the small ubiquitin-like modifier (SUMO) protein family. This protease regulates SUMO pathways by deconjugating sumoylated proteins. This protease also functions to process the precursor SUMO proteins into their mature form. Alternate splicing results in multiple transcript variants.
Gene ID
29843
Gene Name (eCommerce)
SUMO specific peptidase 1
Gene Name (Vector)
SUMO1/sentrin specific peptidase 1
Gene Symbol
SENP1
HGNC ID
HGNC:17927
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1935
ORF Size (bp)
1935 bp
Protein Name (eCommerce)
Sentrin-specific protease 1
RefSeq ID
NM_014554
RefSeq Synonyms
NM_014554, NM_001267595, NM_001267594, BC045639,
Research Areas
Apoptosis
Research Areas (Faceted)
cell_biology
Species
human
Target Sentence
SENP1 (sentrin-specific protease) functions as a protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. Deconjugation of SUMO1 from HDAC1 decreases its transcriptional repression activity. SENP1 also deconjugates SUMO1 from HIPK2 [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q9P0U3].
UniGene ID
Hs.371957
UniProt ID (eCommerce)
Q9P0U3

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.